USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: PDC10_HUMAN USC-OGP 2-DE database:  PDC10_HUMAN PDC10_HUMAN General information about the entry View entry in simple text format Entry name PDC10_HUMAN Primary accession number O14811 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Programmed cell death protein 10; AltName: Full=Cerebral cavernous malformations 3 protein; AltName: Full=TF-1 cell apoptosis-related protein 15;. Gene name Name=PDCD10 Synonyms=CCM3, TFAR15 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0508: pI=6.13; Mw=27085 Cross-references UniProtKB/Swiss-Prot Q9BUL8; PDC10_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PDC10_HUMAN Primary accession number Q9BUL8 Secondary accession number(s) A8K515 D3DNN5 O14811 Sequence was last modified on  June 1, 2001 (version 1) Annotations were last modified on  March 15, 2017 (version 134) Name and origin of the protein Description RecName: Full=Programmed cell death protein 10; AltName: Full=Cerebral cavernous malformations 3 protein; AltName: Full=TF-1 cell apoptosis-related protein 15; Gene name Name=PDCD10 Synonyms=CCM3, TFAR15 Encoded on Name=PDCD10; Synonyms=CCM3, TFAR15 Keywords 3D-structure; Acetylation; Angiogenesis; Apoptosis; Cell membrane; Complete proteome; Cytoplasm; Direct protein sequencing; Golgi apparatus; Membrane; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF022385; AAB72225.1; -; mRNA EMBL CR457107; CAG33388.1; -; mRNA EMBL AK291130; BAF83819.1; -; mRNA EMBL AC079822; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471052; EAW78574.1; -; Genomic_DNA EMBL CH471052; EAW78575.1; -; Genomic_DNA EMBL CH471052; EAW78576.1; -; Genomic_DNA EMBL CH471052; EAW78577.1; -; Genomic_DNA EMBL CH471052; EAW78578.1; -; Genomic_DNA EMBL CH471052; EAW78580.1; -; Genomic_DNA EMBL CH471052; EAW78581.1; -; Genomic_DNA EMBL BC002506; AAH02506.1; -; mRNA EMBL BC016353; AAH16353.1; -; mRNA CCDS CCDS3202.1; -; . RefSeq NP_009148.2; NM_007217.3; . RefSeq NP_665858.1; NM_145859.1; . RefSeq NP_665859.1; NM_145860.1; . RefSeq XP_005247143.1; XM_005247086.4; . RefSeq XP_005247144.1; XM_005247087.4; . RefSeq XP_005247145.1; XM_005247088.3; . RefSeq XP_006713548.1; XM_006713485.3; . RefSeq XP_011510670.1; XM_011512368.2; . RefSeq XP_011510671.1; XM_011512369.2; . RefSeq XP_016861133.1; XM_017005644.1; . UniGene Hs.478150; -; . PDB 3AJM; X-ray; 2.30 A; A/B=8-212 PDB 3L8I; X-ray; 2.50 A; A/B/C/D=1-212 PDB 3L8J; X-ray; 3.05 A; A=14-212 PDB 3RQE; X-ray; 2.80 A; A/B/C/D=1-212 PDB 3RQF; X-ray; 2.70 A; A/B/C/D=1-212 PDB 3RQG; X-ray; 2.50 A; A/B/C/D=1-212 PDB 3W8H; X-ray; 2.43 A; A=8-212 PDB 3W8I; X-ray; 2.40 A; A=8-212 PDB 4GEH; X-ray; 1.95 A; A/C=9-212 PDB 4TVQ; X-ray; 2.80 A; A/B/C/D=1-212 PDBsum 3AJM; -; . PDBsum 3L8I; -; . PDBsum 3L8J; -; . PDBsum 3RQE; -; . PDBsum 3RQF; -; . PDBsum 3RQG; -; . PDBsum 3W8H; -; . PDBsum 3W8I; -; . PDBsum 4GEH; -; . PDBsum 4TVQ; -; . ProteinModelPortal Q9BUL8; -; . SMR Q9BUL8; -; . BioGrid 116400; 58; . DIP DIP-40607N; -; . IntAct Q9BUL8; 35; . MINT MINT-5003501; -; . STRING 9606.ENSP00000376506; -; . iPTMnet Q9BUL8; -; . PhosphoSitePlus Q9BUL8; -; . BioMuta PDCD10; -; . DMDM 74733232; -; . OGP Q9BUL8; -; . EPD Q9BUL8; -; . MaxQB Q9BUL8; -; . PaxDb Q9BUL8; -; . PeptideAtlas Q9BUL8; -; . PRIDE Q9BUL8; -; . TopDownProteomics Q9BUL8; -; . DNASU 11235; -; . Ensembl ENST00000392750; ENSP00000376506; ENSG00000114209; . Ensembl ENST00000461494; ENSP00000420021; ENSG00000114209; . Ensembl ENST00000470131; ENSP00000417202; ENSG00000114209; . Ensembl ENST00000473645; ENSP00000418317; ENSG00000114209; . Ensembl ENST00000497056; ENSP00000420553; ENSG00000114209; . GeneID 11235; -; . KEGG hsa:11235; -; . UCSC uc003fex.5; human; . CTD 11235; -; . DisGeNET 11235; -; . GeneCards PDCD10; -; . GeneReviews PDCD10; -; . HGNC HGNC:8761; PDCD10; . HPA HPA027095; -; . MalaCards PDCD10; -; . MIM 603285; phenotype; . MIM 609118; gene; . neXtProt NX_Q9BUL8; -; . OpenTargets ENSG00000114209; -; . Orphanet 221061; Hereditary cerebral cavernous malformation; . PharmGKB PA33111; -; . eggNOG KOG4025; Eukaryota; . eggNOG ENOG410XTA6; LUCA; . GeneTree ENSGT00390000017913; -; . HOGENOM HOG000007888; -; . HOVERGEN HBG052811; -; . InParanoid Q9BUL8; -; . KO K18269; -; . OMA TMGDETP; -; . OrthoDB EOG091G0JQQ; -; . PhylomeDB Q9BUL8; -; . TreeFam TF105802; -; . SIGNOR Q9BUL8; -; . ChiTaRS PDCD10; human; . EvolutionaryTrace Q9BUL8; -; . GeneWiki PDCD10; -; . GenomeRNAi 11235; -; . PRO PR:Q9BUL8; -; . Proteomes UP000005640; Chromosome 3; . Bgee ENSG00000114209; -; . CleanEx HS_PDCD10; -; . ExpressionAtlas Q9BUL8; baseline and differential; . Genevisible Q9BUL8; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005794; C:Golgi apparatus; IDA:UniProtKB; . GO GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell; . GO GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; . GO GO:0042803; F:protein homodimerization activity; IPI:UniProtKB; . GO GO:0019901; F:protein kinase binding; IPI:UniProtKB; . GO GO:0047485; F:protein N-terminus binding; IPI:UniProtKB; . GO GO:0001525; P:angiogenesis; IEA:UniProtKB-KW; . GO GO:0051683; P:establishment of Golgi localization; IMP:UniProtKB; . GO GO:0090168; P:Golgi reassembly; IMP:UniProtKB; . GO GO:0036481; P:intrinsic apoptotic signaling pathway in response to hydrogen peroxide; IGI:UniProtKB; . GO GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB; . GO GO:1903588; P:negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis; IMP:UniProtKB; . GO GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IMP:UniProtKB; . GO GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB; . GO GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB; . GO GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB; . GO GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB; . GO GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB; . GO GO:0045747; P:positive regulation of Notch signaling pathway; IMP:UniProtKB; . GO GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:UniProtKB; . GO GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IMP:UniProtKB; . GO GO:0032874; P:positive regulation of stress-activated MAPK cascade; IDA:UniProtKB; . GO GO:0050821; P:protein stabilization; IMP:UniProtKB; . GO GO:0042542; P:response to hydrogen peroxide; IDA:UniProtKB; . GO GO:0044319; P:wound healing; spreading of cells; IMP:UniProtKB InterPro IPR009652; PDCD10; . PANTHER PTHR13250; PTHR13250; 1; .

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